1 - 1 of 1 articles
keyword "missing heritability"

The missing heritability problem

The missing heritability problem

In my last post I described the transition from candidate gene studies to genome-wide association studies, and argued that the corresponding change in the methods used, focusing on the whole genome rather than on a handful of genes of presumed biological relevance, has transformed our understanding of the genetic basis of complex traits. In this post I discuss the reasons why, despite this success, we still have not accounted for all the genetic influences we expect to find. / more

filter options

Article (154)
Blog Post (104)
Book Review (43)

facebook